This page details what happened to a number of Seattle or NW based biotech companies that are no longer with us because they were acquired, merged, or folded:

Afya World Medicines merged into IDRI in 2008
Archus Orthopedics ran out of money in September 2009
Argus Genetics LLC, a provider of dog breed DNA testing services, was spun out of the FHCRC and then sold their technology (Wisdom Panel MX) to Mars in 2005
Ascentia Biomedical Corp. did a reverse merger with Fortress Technology Systems in 2006 and changed its name to Duncan Technology Group
Berlex, the US subsidiary of Schering AG, bought Immunex's Leukine in 2002 when Immunex was bought by Amgen. Berlex (as part of Schering AG) was then acquired by Bayer in 2006, who subsequently sold Leukine to Genzyme in 2009
Bristol Meyers Pharmaceutical Research Institute had a site in Seattle, but it was closed down in 1997
CDR Therapeutics went out of business
Cellpro lost a patent lawsuit to Becton Dickinson in 1997. They were forced to divest their Ceprate column to BD, and then went under in 1998
Corixa was acquired by Glaxo Smith Kline in 2006
Corus was acquired by Gilead Sciences in 2006
Cytopeia was purchased by Becton Dickinson in 2008
Darwin Molecular was acquired by Chiroscience in 1996. Chiroscience then merged with Celltech in 1999. Celltech was purchased by UCB in 2004
Eden Bioscience Corp., an agricultural biotech, will be dissolved and liquidated in 2009
Elanex Pharmaceuticals went out of business
Epoch Pharmaceuticals merged into Nanogen in 2004
Genetic Systems was acquired by Bristol Meyers in 1987 for $310M
Homestead Clinical folded in 200?
Icos was acquired by Eli Lilly in 2006 for $2.2B
ID Biomedical, a Vancouver BC based vaccine maker, had a manufacturing facility in Bothell; it was acquired by Glaxo Smith Kline in 2005
Imre changed its focus and its name to Cypress Bioscience in 1996, and moved to San Diego
Immunex was acquired by Amgen in 2002 for $10B. It's first drug Leukine was sold off to Berlex in 2002; Berlex was later acquired by Bayer; Bayer sold Leukine to Genzyme in March 2009
Light Sciences was acquired by Light Sciences Oncology in 2006
Lumera had a microarray technology and transferred its assets to Plexera in 200?
Molecumetics, a subsidiary of Tredegar Industries, went out of business in ???
Nura was acquired by Omeros in 2006
Oculon was acquired by Pharmos Corp. in 1995
Oncogen was acquired by Bristol Myers in 1986
PathoGenesis was acquired by Chiron/Novartis in 2000 for $660M
Plexera Bioscience developed a surface plasmon resonance analysis system but was shut down by Lumera in 2008. Assets were sold to Plexera LLC in 2009, which continues to make a proteomic processor system but is no longer based in the NW.
Receptagen Ltd became Spantel Communications in 2001
Receptech Corp. was spun out from Immunex as a SWORD company in 1989 and was then re-acquired in 1992
Regulome started in 2001 went out of business sometime after 2003
Rhizogenics Corp. on Bainbridge went out of business
Rosetta Inpharmatics is being closed down by Roche in 2009.
Vascular Reconditioning was acquired by Light Sciences Oncology in 2006
VieVax folded in 200?
VizX's software product GeneSifter was sold off to Geospiza in 2008, and VizX shut down
Xcyte Therapies merged into Cyclacel in 2005