Most of the companies listed here are headquartered in the Puget Sound region, although the list also includes other WA State companies and a few in OR and Vancouver, BC.
13Therapeutics - Portland based anti-inflammatory peptide developer
Acucela - Drug therapies for blinding eye diseases
Aequus BioPharma - Genetic polymer technology for biologics
Agave Pharma, Inc. - Unknown business focus
Ajuga Biosciences - Developing terpene based chemicals from mint
Alder Biopharmaceuticals - Yeast monoclonals to treat diseases
Algomedix - Focused on developing medicines for chronic pain
Allon Therapeutics - Focus on neurodegenerative diseases in BC
Allozyne - Protein modification technology to make proteins
Amgen - Multi-national protein-based biotech headquarters in CA
Aminex Therapeutics - Developing inhibitors of polyamine pathway
Amkor Pharma - Virtual biotech, clinical focus on neuroprotection
AmpliPhi - Seattle office of London based bacteriophage company
Anergix LLC - Developing peptide delivery MS treatments; admin office Seattle
Arrowsmith Technologies - Antibodies trap chemo for brain cancer
Artemisia BioMedical - Novel artemisinin-based therapeutics
Artielle Immunotherapeutics - Therapies for autoimmunity in OR
Arzeda - Uses computational approaches to make novel enzymes
Ave Maria (AVM) Biotech - Working on ethical human therapeutics
AVI Biopharma - RNA therapeutics for MD, restenosis, viruses
Beat BioTherapeutics - Working on repairing damaged hearts with stem cells
Bio Architecture Lab - Spinoff from David Baker's lab at the UW
Blaze Bioscience - Developing a “paint” to identify tumor cells
Calcionics - Peptide therapeutics targeting calcification
Cancer Targeted Technology - Unique enzyme inhibitors
Cardeas Pharma - New startup of entrepreneur Bruce Montgomery
Cascade ProDrug - In Eugene, developing anticancer treatments
Celator Pharmaceutics - BC based combination oncology drugs
Cellcyte Genetics - Stem cell expansion bioreactor technology
Cell Therapeutics Inc - Developing small molecules for cancer
Columbia NW Pharmaceuticals - Developing suicide and PTSD treatments
CG Therapeutics - Anti-human chorionic gonadotropin vaccines
CisThera - Drugs for cancer, autoimmune disease, and others
CMC ICOS Biologics - contract biologics manufacturing
Cocrystal Discovery - Small molecule anti-viral drugs
Columbia Northwest Pharmaceuticals - Suicide prevention
CompleGen - Functional genetics for drug discovery
Compliment Corp - Website under construction
Coronado Biosciences - Clinical stage cancer care company
Covance - Acquired Rosetta's gene expression laboratory
Dendreon - Vaccines for prostate cancer and other cancers
DesignMedix - Portland based drug combination company
Dimera - Portland based, discovering novel medical concepts
Emerald Biostructures - Contract protein crystallization services
Emergent BioSolutions - Developing small modular immunopharmaceuticals acquired from Trubion as well as vaccines
Etubics - Developing vector vaccines for infectious diseases
Fate Therapeutics - Stem cell based therapies with HQ in CA
Floragenex - SNP discovery and genotyping in plants
Gamma Therapeutics - OHSU hematology/cardiology startup
Genzyme - Manufactures and sells Leukine in US, HQ in MA
Gilead - Lung disease discovery group in Seattle; HQ in CA
Groove Biopharma (formerly Mirina) - Uses microRNA to develop new drugs
Halo-Bio RNAi Therapeutics - Novel asymmetric RNAi therapeutics
Helix BioMedix - Bioactive peptides for skin disorders, infections
HemaQuest - Developing therapeutics for blood diseases
Icogenex - Drug discovery via high throughput proteomic screens
Ikaria - Focus on metabolic depression and critical care medicine
ImaRxTherapeutics - Blood clot dissolving technology
Imdaptive - Profiles changes in the adaptive immune system
Immune Design - Developing therapeutics for infectious diseases
Immusoft - Technology platform to reprogram the immune system
Implicit Bioscience - Small molecule dipeptides as anti-microbials
Inimex Pharmaceuticals - Works on innate defense regulators (Canadian?)
Indel Therapeutics - Working on novel antibiotics
ISM Therapeutics - Therapeutics based on inositol signaling
Kaleetan Pharmaceuticals - Vaccine focused startup
KinDex Therapeutics - Focus on metabolic regulatory networks
Kineta - Small molecule drugs that enhance immunity
Koronis - Developing anti-viral drugs via viral decay methodologies
Light Sciences Oncology - Light activated oncology products
LigoCyte Therapeutics - Vaccine technologies based in MT
M3 Biotechnology, Inc. - Regulating protein-protein interactions, based in Tumwater
Marina Biotech - (formerly MDRNA) RNAi based company
Matrix Genetics - Engineering algae to make oil
Mediquest Therapeutics - Topical treatments for diseases
Microsoft Amalga Life Sciences - Life sciences software business
Mitotherix - FHCRC spinoff working on anti-cancer therapies
NanoQuantum - Works on photodynamic nanoparticles
Najit - Diagnostics, vaccines for developing countries; in Portland
NeuMedics - Developing drug to prevent Azheimer’s symptoms
North Coast Biologics - Rabbit high-affinity antibody based drugs
Novo Nordisk - Branch of Danish pharma focusing on immunity
NW Biotherapeutics - Dendritic cell based cancer vaccines
Obenomics - Small molecule approach to treating obesity
Omeros - Clinical stage company, focus is on inflammation, CNS
Oncofactor - Accelerator startup focused on novel cancer therapy
Oncogenex - Small molecule based oncology drug pipeline
OncoMed Pharma - Therapies directed at cancer stem cells
Oncothyreon (formerly Biomira) - Oncology drugs and vaccines
Ondine Research - Vancouver CA based anti-infective therapies
Onkor Pharmaceuticals - Virtual company making cancer drugs
Pacific Northwest Biotechnology - Small molecule drug discovery
PharmIn - Copolymer drug delivery platform technology
PhaseRx - Multi-functional polymers to aid drug delivery
PhotoMedex - Skin care products using copper peptide technology
Poniard was to be acquired by Allozyne in 2011 in order to acquire a listing on the NASDAQ and thereby go public. However, the deal did not go through and was terminated Dec. 22, 2011
Precision Genome Engineering - Making genomic changes and custom organisms
ProFibrix - Drugs for hemostasis and regenerative medicine
ProteoTech - Small molecule development for amyloid diseases
Protein Advances Inc - Bioinformatics based vaccine discovery
Qwell - Developing small molecule drugs from plant sources
Rasiris - Montana company developing breast cancer drugs
Recodagen - Targets mechanisms that allow cancer metastasis
Resolve Therapeutics - Start up developing a lupus drug
Revalesio Corporation - Developing treatments for inflammatory disease
Scolr Pharma - Controlled drug delivery technology development
Seattle Genetics - Monoclonal antibodies for cancer treatment
Seattle Life Sciences - Zymogenetics spin-off in 2009
Seredigm - Biological therapeutics for ischemia/reperfusion injury
Sound Pharmaceuticals - Drugs to prevent hearing loss
Spiral Genetics - Open source based bioinformatics products
Syntrix Biosystems - Novel therapeutics and research platforms
TapImmune - Developing vaccines for oncology and infections
Tekmira - RNAi drugs for cancer and cholesterol; BC based
Theraclone Sciences (was Spaltudaq) - Therapeutic antibodies
TherEpi Corporation - Epigenetic drug discovery focus
The Gene Pool, Inc - Molecular locks based drug discovery
Valocor Therapeutics - BC based dermatology drug developer
V-Gene - Antibody based drug development
Viva Biopharm - Manufacturing plant in Blaine for BC company
VentiRx - Developing new small molecule drugs for cancer, ID
Visient Therapeutics - Vision focused subsidiary of Light Sciences
VLST - Discovers new drug targets based on virus interactions
WA 32609 - Holding company, acquired ischemic stroke therapy
Xori - Making antibodies in chicken cells for faster, cheaper drugs
Zymeworks - BC based computational biology drug platform
