For the benefit of the local biotech community, I have assembled an updated list of Northwest (mostly Puget Sound) drug-centered biotechnology companies. Also included here are companies headquartered elsewhere, but with research or manufacturing groups in our area. Publicly traded companies are in Bold. Hyperlinks will take you to the company websites; no hyperlink means no website. Please e-mail me any corrections or updates. Click here to see a list of these companies sorted by the technological approaches they have taken towards drug development. Click here to go to my Seattle Biotech Graveyard page detailing the fates of companies that are no longer with us in Seattle. Finally, click here to learn about my consulting services, or use the links on the left.

There are a total of 103 companies listed in alphabetical order here, of which 21 are publicly traded:
Acucela - Drug therapies for blinding eye diseases
Adaptive TCR - Focus on T-cell diversity, adaptive immune response
Aequus BioPharma - Genetic polymer technology for biologics
Ajuga Biosciences - Developing terpene based chemicals from mint
Alder Biopharmaceuticals - Yeast monoclonals to treat diseases
Algomedix - Focused on developing medicines for chronic pain
Allon Therapeutics - Focus on neurodegenerative diseases in BC
Allozyne - Protein modification technology to make proteins
Amgen - Multi-national protein-based biotech headquartered in CA
Aminex Therapeutics - Developing inhibitors of polyamine pathway
Amkor Pharma - Virtual biotech, clinical focus on neuroprotection
Arrowsmith Technologies - Antibodies trap chemo for brain cancer
Artemisia BioMedical - Novel artemisinin-based therapeutics
Artielle Immunotherapeutics - Therapies for autoimmunity in OR
Arzeda - Uses computational approaches to make novel enzymes
Ave Maria (AVM) Biotech - Working on ethical human therapeutics
AVI Biopharma - RNA therapeutics for MD, restenosis, viruses
Beat BioTherapeutics - Working on repairing damaged hearts with stem cells
Bio Architecture Lab - Spinoff from David Baker's lab at the UW
Calcionics - Peptide therapeutics targeting calcification
Calistoga Pharmaceuticals - Developing PI3 kinase inhibitors
Cancer Targeted Technology - Unique enzyme inhibitors
Cascade ProDrug - In Eugene, developing anticancer treatments
Celator Pharmaceutics - BC based combination oncology drugs
Cellcyte Genetics - Stem cell expansion bioreactor technology
CG Therapeutics - Anti-human chorionic gonadotropin vaccines
CisThera - Drugs for cancer, autoimmune disease, and others
CMC ICOS Biologics - contract biologics manufacturing
Cocrystal Discovery - Small molecule anti-viral drugs
CompleGen - Functional genetics for drug discovery
Coronado Biosciences - Clinical stage cancer care company
Covance - Acquired Rosetta's gene expression laboratory
Cell Therapeutics Inc - Biologics and small molecules for cancer
Dendreon - Vaccines for prostate cancer and other cancers
DesignMedix - Portland based drug combination company
Dimera - Portland based, discovering novel medical concepts
Emerald Biostructures - Contract protein crystallization services
Etubics - Developing vector vaccines for infectious diseases
Fate Therapeutics - Stem cell based therapies with HQ in CA
Floragenex - SNP discovery and genotyping in plants
Gamma Therapeutics - OHSU hematology/cardiology startup
Genzyme - Manufactures and sells Leukine in US, HQ in MA
Gilead - Lung disease discovery group in Seattle; HQ in CA
Halo-Bio - Novel asymmetric RNAi therapeutics
Helix BioMedix - Bioactive peptides for skin disorders, infections
HemaQuest - Developing therapeutics for blood diseases
Icogenex - Drug discovery via high throughput proteomic screens
Ikaria - Focus on metabolic depression and critical care medicine
ImaRxTherapeutics - Blood clot dissolving technology
Imdaptive - Profiles changes in the adaptive immune system
Immune Design - Developing therapeutics for infectious diseases
Immusoft - Technology platform to reprogram the immune system
Implicit Bioscience - Small molecule dipeptides as anti-microbials
Indel Therapeutics - Working on novel antibiotics
ISM Therapeutics - Therapeutics based on inositol signaling
Kaleetan Pharmaceuticals - Vaccine focused startup
KinDex Therapeutics - Focus on metabolic regulatory networks
Kineta - Small molecule drugs that enhance immunity
Koronis - Developing anti-viral drugs via viral decay methodologies
Light Sciences Oncology - Light activated oncology products
LigoCyte Therapeutics - Vaccine technologies based in MT
Marina Biotech - (formerly MDRNA) RNAi based company
Mediquest Therapeutics - Topical treatments for diseases
Microsoft Amalga Life Sciences - Life sciences software business
Mirina - Uses microRNA to develop new drugs
Najit - Diagnostics, vaccines for developing countries; in Portland
North Coast Biologics - Rabbit high-affinity antibody based drugs
Novo Nordisk - Branch of Danish pharma focusing on immunity
NW Biotherapeutics - Dendritic cell based cancer vaccines
Obenomics - Small molecule approach to treating obesity
Omeros - Clinical stage company, focus is on inflammation, CNS
Oncogenex - Small molecule based oncology drug pipeline
OncoMed Pharma - Therapies directed at cancer stem cells
Onkor Pharmaceuticals - Virtual company making cancer drugs
Oncothyreon (formerly Biomira) - Oncology drugs and vaccines
Pacific Northwest Biotechnology - Small molecule drug discovery
PharmIn - Copolymer drug delivery platform technology
PharmSelex - Developing G-protein coupled receptor based drugs
PhaseRx - Multi-functional polymers to aid drug delivery
Poniard (was NeoRx) - Developing oncology products; HQ in CA
Presage Therapeutics - Screen cancer drugs in vivo for efficacy
Procyte - Skin care products using copper peptide technology
ProFibrix - Drugs for hemostasis and regenerative medicine
ProteoTech - Small molecule development for amyloid diseases
Protein Advances Inc - Bioinformatics based vaccine discovery
Primal - Focus on G-protein coupled receptors
Qwell - Developing small molecule drugs from plant sources
Rasiris - Montana company developing breast cancer drugs
Recodagen - Targets mechanisms that allow cancer metastasis
Scolr Pharma - Controlled drug delivery technology development
Seattle Genetics - Monoclonal antibodies for cancer treatment
Seattle Life Sciences - Zymogenetics spin-off in 2009
Seredigm - Biological therapeutics for ischemia/reperfusion injury
Sound Pharmaceuticals - Drugs to prevent hearing loss
Syntrix Biosystems - Novel therapeutics and research platforms
TapImmune - Developing vaccines for oncology and infections
Targeted Genetics - Gene therapy based drug company
Tekmira - RNAi drugs for cancer and cholesterol; BC based
Theraclone Sciences (was Spaltudaq) - Therapeutic antibodies
TherEpi Corporation - Epigenetic drug discovery focus
The Gene Pool, Inc - Molecular locks based drug discovery
Trubion - Developing small modular immunopharmaceuticals
Valocor Therapeutics - BC based dermatology drug developer
Viva Biopharm - Manufacturing plant in Blaine for BC company
VentiRx - Developing new small molecule drugs for cancer, ID
Visient Therapeutics - Vision focused subsidiary of Light Sciences
VLST - Discovers new drug targets based on virus interactions
WA 32609 - Holding company, acquired ischemic stroke therapy
Xori - Making antibodies in chicken cells for faster, cheaper drugs
Zymeworks - BC based computational biology drug platform
Zymogenetics - Discovers and markets novel protein drugs